The principal cytochrome P450 isoenzyme involved appears for being CYP2E1, with CYP1A2 and CYP3A4 as more pathways. Somewhere around eighty five% of the oral dose seems during the urine inside of 24 hours of administration, most as being the glucuronide conjugate, with modest quantities of other conjugates and unchanged drug (see OVERDOSAGE) for to